|BioSocial Methods Newsletter – September 2014 – Issue #4|
BioSocial Methods Collaborative Member
Richard G. Cornell Distinguished University Professor of Biostatistics
Director, Center for Statistical Genetics
Director, Genome Science Training Program
Member of the Institute of Medicine of the National Academy of Sciences
Fellow of the American Statistical Association
Fellow of the American Association for the Advancement of Science.
|Perspectives of a statistical geneticistI study the genetic basis of human disease using statistical methods, including techniques like genome-wide association (GWA). I lead several studies to identify genetic variations that predispose individuals to type 2 diabetes. In one such study, we have sequenced the portion of the genome that codes for protein in 13,000 people from different cultural origins: Europeans, Africans, Hispanics, East Asians and South Asians, and we are now extending that study to another 25,000 individuals. I am also working on a project focused on the genetics of bipolar disease in which we are sequencing the genomes of 4,000 European participants, and on a study of bipolar disorder and schizophrenia in which we plan to sequence the genomes of 10,000 individuals of European, African and Hispanic descent. To do this type of work successfully necessitates collaborating extensively with others.
What are the barriers to integrating genetics and behavioral science?
Simple Genomes/Complex Phenotypes – Cost Effective Studies – Big Data
We are pleased to announce Colter Mitchell is the new Associate Director of the BioSocial Methods Collaborative
Faculty Research Fellow, Survey Research Center, University of Michigan
|2014 Report from NIH/NIA re: Division of Behavioral and Social Research (BSR)Going forward, BSR is encouraged to expand its portfolio of theoretically driven research on mechanistic and biological links to personal and social behavior by 1) broadening the range of biomeasures to include additional cellular and molecular hallmarks of aging and 2) identifying important biomarkers to harmonize that are linked to aging-relevant social and behavioral phenomena, including the integration of neuroimaging data (resting state, structural, and functional) in large-scale surveys and laboratory-based studies with representative samples. In addition, BSR should support method development to optimize the comparison and integration of heterogeneous data sets, both within and across populations. Click here for NIH/NIA report.|
Members in the News!
Kira Birditt – September 5, 2014
Parental depression and neuroticism may exert an influence on offspring’s development of rumination, which may increase offspring’s risk for depression.
Ethan Kross – July 25, 2014
Dr. Ethan Kross, director of the Emotion and Self-Control Laboratory, at the University of Michigan, was quoted in a New York Times story about how far people will go to avoid introspection.
Kenneth Langa – July 15, 2014
Dr. Kenneth Langa, professor of internal medicine, gerontology and health management and policy, was quoted in a story about falling rates of Alzheimer’s disease and other forms of dementia in the U.S.
James Jackson – June 23, 2014
President Obama announced his intention to appoint University of Michigan social psychologist James Jackson to the National Science Board of the National Science Foundation.