Gene/Environment Interactions with Brain as Mediator: An interview with BioSocial Methods Collaborative Luke Hyde
Much of the research I am currently most excited about is examining the brain as a mediator of gene-environment interactions. I have written about these types of models theoretically and we are currently analyzing data to examine this very question, particularly in relation to child development and psychopathology. We know that individual differences in genes, as well as our experiences, can increase risk for psychopathology and also likely affect the structure and function of our brain. However, little work has actually examined how interactions between well-measures experiences and specific genetic polymorphisms are linked to differences in brain function and subsequent behavior, particularly as this process unfolds across development.